This is the closest casino to Louisville because casino gambling is not allowed in neighboring Floyd County. It is located outside the community of Elizabeth, Indiana at the Harrison County line, across the Ohio River from Louisville, Kentucky. Opened in 1998, it is owned by Vici Properties and operated by the Eastern Band of Cherokee Indians, using the Caesars name under license from Caesars Entertainment. Caesars Southern Indiana (formerly Caesars Indiana and Horseshoe Southern Indiana ) is a casino hotel in Southern Indiana.